Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50174577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50174577 (CHEMBL3810334) Show SMILES Oc1c[nH]c(COC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1=O |r| Show InChI InChI=1S/C23H22N2O6/c26-20-12-18(24-13-21(20)27)15-30-22(28)19(11-16-7-3-1-4-8-16)25-23(29)31-14-17-9-5-2-6-10-17/h1-10,12-13,19,27H,11,14-15H2,(H,24,26)(H,25,29)/t19-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin) assessed as reduction in monophenolase activity				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50174577 (CHEMBL3810334) Show SMILES Oc1c[nH]c(COC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1=O |r| Show InChI InChI=1S/C23H22N2O6/c26-20-12-18(24-13-21(20)27)15-30-22(28)19(11-16-7-3-1-4-8-16)25-23(29)31-14-17-9-5-2-6-10-17/h1-10,12-13,19,27H,11,14-15H2,(H,24,26)(H,25,29)/t19-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin) assessed as reduction in monophenolase activity				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50174577 (CHEMBL3810334) Show SMILES Oc1c[nH]c(COC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1=O |r| Show InChI InChI=1S/C23H22N2O6/c26-20-12-18(24-13-21(20)27)15-30-22(28)19(11-16-7-3-1-4-8-16)25-23(29)31-14-17-9-5-2-6-10-17/h1-10,12-13,19,27H,11,14-15H2,(H,24,26)(H,25,29)/t19-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activity				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50174577 (CHEMBL3810334) Show SMILES Oc1c[nH]c(COC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1=O |r| Show InChI InChI=1S/C23H22N2O6/c26-20-12-18(24-13-21(20)27)15-30-22(28)19(11-16-7-3-1-4-8-16)25-23(29)31-14-17-9-5-2-6-10-17/h1-10,12-13,19,27H,11,14-15H2,(H,24,26)(H,25,29)/t19-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activity				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair