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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50559076'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Homo sapiens (Human))
BDBM50559076
PNG
(CHEMBL4743159)
Show SMILES CC(C)C(=O)Nc1nc(cs1)-c1ccc(O)cc1O
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
250n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysis


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00994
BindingDB Entry DOI: 10.7270/Q2PV6Q29
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50559076
PNG
(CHEMBL4743159)
Show SMILES CC(C)C(=O)Nc1nc(cs1)-c1ccc(O)cc1O
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1.10n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50559076
PNG
(CHEMBL4743159)
Show SMILES CC(C)C(=O)Nc1nc(cs1)-c1ccc(O)cc1O
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assay


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00994
BindingDB Entry DOI: 10.7270/Q2PV6Q29
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50559076
PNG
(CHEMBL4743159)
Show SMILES CC(C)C(=O)Nc1nc(cs1)-c1ccc(O)cc1O
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human tyrosinase assessed as reduction in L-dopaquinone-MBTH complex formation using L-DOPA as substrate measured for 10 mins by spectr...


Citation and Details

Article DOI: 10.1039/d0md00310g
BindingDB Entry DOI: 10.7270/Q2K0780V
More data for this
Ligand-Target Pair