Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM50425783'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50425783 (CHEMBL2316579) Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3ccc4[nH]ncc4c3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C30H28F3N5O/c1-20-3-6-23(16-22(20)7-4-21-5-10-28-25(15-21)18-34-36-28)29(39)35-26-9-8-24(27(17-26)30(31,32)33)19-38-13-11-37(2)12-14-38/h3,5-6,8-10,15-18H,11-14,19H2,1-2H3,(H,34,36)(H,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant wild type ABL1 expressed in insect cells after 30 mins by FRET assay				J Med Chem 56: 879-94 (2013) Article DOI: 10.1021/jm301581y BindingDB Entry DOI: 10.7270/Q2V40WH7
					More data for this Ligand-Target Pair