Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ABL1 [T315I] (Homo sapiens (Human)) | BDBM50322535 (3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
NANJING SANHOME PHARMACEUTICAL CO., LTD. US Patent | Assay Description Serially diluting the compound of the present invention from 1 uM initial concentration in three-fold fashion and formulating 10 concentrations (50.8... | US Patent US9255107 (2016) BindingDB Entry DOI: 10.7270/Q22806F9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |