Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM120746'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM120746 (US8703767, 6) Show SMILES C=CC(=O)Nc1cccc(c1)-c1nc(Nc2ccc(cc2)N2CCOCC2)ncc1Nc1ccccc1 Show InChI InChI=1S/C29H28N6O2/c1-2-27(36)32-24-10-6-7-21(19-24)28-26(31-22-8-4-3-5-9-22)20-30-29(34-28)33-23-11-13-25(14-12-23)35-15-17-37-18-16-35/h2-14,19-20,31H,1,15-18H2,(H,32,36)(H,30,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...				US Patent US8703767 (2014) BindingDB Entry DOI: 10.7270/Q23X85BF
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