Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM134230'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM134230 (US8846673, 113) Show SMILES Nc1n[nH]c2c(ncc(-c3ccc(Oc4ccccc4)cc3)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H17F3N4O2/c26-25(27,28)34-19-8-4-5-16(13-19)22-23-21(24(29)32-31-23)20(14-30-22)15-9-11-18(12-10-15)33-17-6-2-1-3-7-17/h1-14H,(H3,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	7.4	0
Bristol-Myers Squibb Company US Patent					Assay Description To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 uM), ATP (2...				US Patent US8846673 (2014) BindingDB Entry DOI: 10.7270/Q26M35HM
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