Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM134240'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM134240 (US8846673, 219) Show SMILES Nc1n[nH]c2cc(nc(-c3ccc(Oc4ccccc4)cc3)c12)-c1ccc(cc1)C(=O)NCC(O)=O Show InChI InChI=1S/C27H21N5O4/c28-26-24-22(31-32-26)14-21(16-6-8-18(9-7-16)27(35)29-15-23(33)34)30-25(24)17-10-12-20(13-11-17)36-19-4-2-1-3-5-19/h1-14H,15H2,(H,29,35)(H,33,34)(H3,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	0
Bristol-Myers Squibb Company US Patent					Assay Description To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 uM), ATP (2...				US Patent US8846673 (2014) BindingDB Entry DOI: 10.7270/Q26M35HM
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