Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM149468'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM149468 (US8975260, 115) Show SMILES Cc1cc(Nc2cc(n[nH]c2=O)-c2cccc(N3Cc4cc(sc4C3=O)C(C)(C)C)c2C)no1 Show InChI InChI=1S/C25H25N5O3S/c1-13-9-21(29-33-13)26-18-11-17(27-28-23(18)31)16-7-6-8-19(14(16)2)30-12-15-10-20(25(3,4)5)34-22(15)24(30)32/h6-11H,12H2,1-5H3,(H,28,31)(H,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	n/a
Genetech, Inc; Gilead Connecticut, Inc. US Patent					Assay Description A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...				US Patent US8975260 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DW9
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