Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM174597'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM174597 (US9688676, 32 (R)-2-(3-(6-amino-8-oxo-7-(4-phenoxy...) Show SMILES CC1(CCN(CC1)C1COC1)C=C(C#N)C(=O)N1CCC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O |r,w:11.12| Show InChI InChI=1S/C35H38N8O4/c1-35(13-16-40(17-14-35)27-21-46-22-27)18-24(19-36)33(44)41-15-5-6-26(20-41)43-32-30(31(37)38-23-39-32)42(34(43)45)25-9-11-29(12-10-25)47-28-7-3-2-4-8-28/h2-4,7-12,18,23,26-27H,5-6,13-17,20-22H2,1H3,(H2,37,38,39)/t26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	25
PRINCIPIA BIOPHARMA INC. US Patent					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of BTK kinase activity of a compound of the pre...				US Patent US9688676 (2017) BindingDB Entry DOI: 10.7270/Q2XD0ZVX
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM174597 (US9688676, 32 (R)-2-(3-(6-amino-8-oxo-7-(4-phenoxy...) Show SMILES CC1(CCN(CC1)C1COC1)C=C(C#N)C(=O)N1CCC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O |r,w:11.12| Show InChI InChI=1S/C35H38N8O4/c1-35(13-16-40(17-14-35)27-21-46-22-27)18-24(19-36)33(44)41-15-5-6-26(20-41)43-32-30(31(37)38-23-39-32)42(34(43)45)25-9-11-29(12-10-25)47-28-7-3-2-4-8-28/h2-4,7-12,18,23,26-27H,5-6,13-17,20-22H2,1H3,(H2,37,38,39)/t26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	25
PRINCIPIA BIOPHARMA INC. US Patent					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of BTK kinase activity of a compound of the pre...				US Patent US9688676 (2017) BindingDB Entry DOI: 10.7270/Q2XD0ZVX
					More data for this Ligand-Target Pair