Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM174858'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM174858 (US9688676, 65 (R)-2-(3-(4-amino-2-oxo-3-(4-phenoxy...) Show SMILES CCC1(CCOCC1)\C=C(\C#N)C(=O)N1CCC[C@H](C1)n1c2ccnc(N)c2n(-c2ccc(Oc3ccccc3)c(F)c2)c1=O |r| Show InChI InChI=1S/C34H35FN6O4/c1-2-34(13-17-44-18-14-34)20-23(21-36)32(42)39-16-6-7-25(22-39)40-28-12-15-38-31(37)30(28)41(33(40)43)24-10-11-29(27(35)19-24)45-26-8-4-3-5-9-26/h3-5,8-12,15,19-20,25H,2,6-7,13-14,16-18,22H2,1H3,(H2,37,38)/b23-20-/t25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	25
PRINCIPIA BIOPHARMA INC. US Patent					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of BTK kinase activity of a compound of the pre...				US Patent US9688676 (2017) BindingDB Entry DOI: 10.7270/Q2XD0ZVX
					More data for this Ligand-Target Pair