Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM235165'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM235165 (US9359345, 11) Show SMILES NC(=O)c1nc(sc1Nc1ccccn1)N1CCC[C@H](C1)NC(=O)CNc1cccc(Cl)c1 |r| Show InChI InChI=1S/C22H24ClN7O2S/c23-14-5-3-6-15(11-14)26-12-18(31)27-16-7-4-10-30(13-16)22-29-19(20(24)32)21(33-22)28-17-8-1-2-9-25-17/h1-3,5-6,8-9,11,16,26H,4,7,10,12-13H2,(H2,24,32)(H,25,28)(H,27,31)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.37E+3	n/a	n/a	n/a	n/a	7.15	14
HOFFMANN-LA ROCHE INC. US Patent					Assay Description This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...				US Patent US9359345 (2016) BindingDB Entry DOI: 10.7270/Q2668C21
					More data for this Ligand-Target Pair