Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM250008'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM250008 (US9447106, 133a (peak 1)) Show SMILES COc1cc(ccc1C)-c1nn2[C@H](CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C |r| Show InChI InChI=1S/C24H25N5O3/c1-4-20(30)27-17-8-6-5-7-16(17)18-11-12-26-24-21(23(25)31)22(28-29(18)24)15-10-9-14(2)19(13-15)32-3/h4-10,13,18,26H,1,11-12H2,2-3H3,(H2,25,31)(H,27,30)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	25
BeiGene, Ltd. US Patent					Assay Description Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...				US Patent US9447106 (2016) BindingDB Entry DOI: 10.7270/Q21Z439C
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