Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM259847'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM259847 (US9505766, 51) Show SMILES NC(=O)C(=C\c1cccc(c1)-n1cc(-c2ccc(Cl)cc2)c2c(N)ncnc12)\C#N Show InChI InChI=1S/C22H15ClN6O/c23-16-6-4-14(5-7-16)18-11-29(22-19(18)20(25)27-12-28-22)17-3-1-2-13(9-17)8-15(10-24)21(26)30/h1-9,11-12H,(H2,26,30)(H2,25,27,28)/b15-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US Patent					Assay Description Btk (human, full length) was purchased (Invitrogen, catalog number PV3363) and used as specified in the product literature. Btk (2 nM final concentra...				US Patent US9505766 (2016) BindingDB Entry DOI: 10.7270/Q2639NPR
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