Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM267501'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM267501 (4-(8-amino-3-(tetrahydro-2H-pyran-4-yl)imidazo[1,5...) Show SMILES CCCc1ccnc(NC(=O)c2ccc(cc2)-c2nc([C@@H]3[C@H]4COC[C@@H]34)n3ccnc(N)c23)c1 |r| Show InChI InChI=1S/C26H26N6O2/c1-2-3-15-8-9-28-20(12-15)30-26(33)17-6-4-16(5-7-17)22-23-24(27)29-10-11-32(23)25(31-22)21-18-13-34-14-19(18)21/h4-12,18-19,21H,2-3,13-14H2,1H3,(H2,27,29)(H,28,30,33)/t18-,19+,21+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	7.2	25
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V. US Patent					Assay Description Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below. Btk enzyme (...				US Patent US9718828 (2017) BindingDB Entry DOI: 10.7270/Q2H9977T
					More data for this Ligand-Target Pair