Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM267507'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM267507 (4-(8-amino-3-(2,2-dimethyltetrahydro-2H-pyran-4-yl...) Show SMILES CCCc1ccnc(NC(=O)c2ccc(cc2)-c2nc(C3CCOC(C)(C)C3)n3ccnc(N)c23)c1 Show InChI InChI=1S/C28H32N6O2/c1-4-5-18-10-12-30-22(16-18)32-27(35)20-8-6-19(7-9-20)23-24-25(29)31-13-14-34(24)26(33-23)21-11-15-36-28(2,3)17-21/h6-10,12-14,16,21H,4-5,11,15,17H2,1-3H3,(H2,29,31)(H,30,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	7.2	25
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V. US Patent					Assay Description Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below. Btk enzyme (...				US Patent US9718828 (2017) BindingDB Entry DOI: 10.7270/Q2H9977T
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