Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM316841'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM316841 (US9617260, Compound 2 | benzyl N-[3- [3-(prop-2- e...) Show SMILES C=CC(=O)Nc1cccc(c1)-c1c[nH]c2ncc(NC(=O)OCc3ccccc3)cc12 Show InChI InChI=1S/C24H20N4O3/c1-2-22(29)27-18-10-6-9-17(11-18)21-14-26-23-20(21)12-19(13-25-23)28-24(30)31-15-16-7-4-3-5-8-16/h2-14H,1,15H2,(H,25,26)(H,27,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluoresence...				US Patent US9617260 (2017) BindingDB Entry DOI: 10.7270/Q28W3GCX
					More data for this Ligand-Target Pair