Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM316867'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM316867 ((3- fluorophenyl) methyl N-[3- [1-(2- oxobutanoyl)...) Show SMILES CCC(=O)C(=O)N1CCC(=CC1)c1c[nH]c2ncc(NC(=O)OCc3cccc(F)c3)cc12 |c:9| Show InChI InChI=1S/C24H23FN4O4/c1-2-21(30)23(31)29-8-6-16(7-9-29)20-13-27-22-19(20)11-18(12-26-22)28-24(32)33-14-15-4-3-5-17(25)10-15/h3-6,10-13H,2,7-9,14H2,1H3,(H,26,27)(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluoresence...				US Patent US9617260 (2017) BindingDB Entry DOI: 10.7270/Q28W3GCX
					More data for this Ligand-Target Pair