Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM350150'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM350150 ((1S,3R)-3-[8-amino-1-(4- {(1R)-1-hydroxy-1-[3- (tr...) Show SMILES C[C@@](O)(c1ccc(cc1)-c1nc(n2ccnc(N)c12)[C@]1(C)CC[C@@](C)(C1)C(O)=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C29H29F3N4O3/c1-26(11-12-27(2,16-26)25(37)38)24-35-21(22-23(33)34-13-14-36(22)24)17-7-9-18(10-8-17)28(3,39)19-5-4-6-20(15-19)29(30,31)32/h4-10,13-15,39H,11-12,16H2,1-3H3,(H2,33,34)(H,37,38)/t26-,27+,28-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...				US Patent US10208047 (2019) BindingDB Entry DOI: 10.7270/Q2M32XWT
					More data for this Ligand-Target Pair