Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM351763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351763 (US9796716, Compound 9) Show SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cccc(OCc5ccc(Cl)cc5)c4)cc3)c12)C1CCCC1 Show InChI InChI=1S/C29H26ClN5O2/c30-21-12-8-19(9-13-21)17-36-24-6-3-7-25(16-24)37-23-14-10-20(11-15-23)27-26-28(31)32-18-33-29(26)35(34-27)22-4-1-2-5-22/h3,6-16,18,22H,1-2,4-5,17H2,(H2,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
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