Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM351768'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351768 (US9796716, Compound 14) Show SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cccc(OCc5cncs5)c4)cc3)c12)C1CCCC1 Show InChI InChI=1S/C26H24N6O2S/c27-25-23-24(31-32(18-4-1-2-5-18)26(23)30-15-29-25)17-8-10-19(11-9-17)34-21-7-3-6-20(12-21)33-14-22-13-28-16-35-22/h3,6-13,15-16,18H,1-2,4-5,14H2,(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
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