Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM351775'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351775 (US9796716, Compound 21) Show SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cccc(OCc5ccccc5)c4)cc3)c12)C1CCOCC1 Show InChI InChI=1S/C29H27N5O3/c30-28-26-27(33-34(29(26)32-19-31-28)22-13-15-35-16-14-22)21-9-11-23(12-10-21)37-25-8-4-7-24(17-25)36-18-20-5-2-1-3-6-20/h1-12,17,19,22H,13-16,18H2,(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
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