Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM351807'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351807 (US9796716, Compound 51) Show SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cccc(OCc5cncs5)c4)cc3)c12)C1CCCNC1 Show InChI InChI=1S/C26H25N7O2S/c27-25-23-24(32-33(26(23)31-15-30-25)18-3-2-10-28-12-18)17-6-8-19(9-7-17)35-21-5-1-4-20(11-21)34-14-22-13-29-16-36-22/h1,4-9,11,13,15-16,18,28H,2-3,10,12,14H2,(H2,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
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