Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM384225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM384225 (US10280184, Example C.1.1) Show SMILES C=CC(=O)NCc1cccc(c1)-c1cn2ncnc2c(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C25H25N7O2/c1-2-23(33)26-15-18-4-3-5-19(14-18)22-16-32-25(27-17-28-32)24(30-22)29-20-6-8-21(9-7-20)31-10-12-34-13-11-31/h2-9,14,16-17H,1,10-13,15H2,(H,26,33)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University					Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...				J Med Chem 51: 6725-39 (2008) BindingDB Entry DOI: 10.7270/Q2PR7Z9P
					More data for this Ligand-Target Pair