Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM390039'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM390039 (US10323037, Example 52 | US9951077, 52) Show SMILES COc1ccc(cc1)-c1cn(C2CCCN(C2)C(=O)\C=C\CN(C)C)c2c1c(N)n[nH]c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
JIANGSU HENGRUI MEDICINE CO., LTD. US Patent					Assay Description The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...				US Patent US10323037 (2019) BindingDB Entry DOI: 10.7270/Q2W098BW
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM390039 (US10323037, Example 52 | US9951077, 52) Show SMILES COc1ccc(cc1)-c1cn(C2CCCN(C2)C(=O)\C=C\CN(C)C)c2c1c(N)n[nH]c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...				Bioorg Med Chem Lett 17: 3972-7 (2007) BindingDB Entry DOI: 10.7270/Q2MG7RV0
					More data for this Ligand-Target Pair