Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM390099'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM390099 (US9951077, 111) Show SMILES CC#CC(=O)N1CC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12 Show InChI InChI=1S/C25H22N6O3/c1-2-6-20(32)30-14-13-17(15-30)31-23-21(24(26)27-28-25(23)33)22(29-31)16-9-11-19(12-10-16)34-18-7-4-3-5-8-18/h3-5,7-12,17H,13-15H2,1H3,(H2,26,27)(H,28,33)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...				Bioorg Med Chem Lett 17: 3972-7 (2007) BindingDB Entry DOI: 10.7270/Q2MG7RV0
					More data for this Ligand-Target Pair