Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM397247'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM397247 (US10596172, Compound I-204 | US10828300, Compound ...) Show SMILES Fc1cnc(Nc2cccc(OCCCn3ccnc3)c2)nc1Nc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C25H24FN7O2/c1-2-23(34)29-18-6-3-7-19(14-18)30-24-22(26)16-28-25(32-24)31-20-8-4-9-21(15-20)35-13-5-11-33-12-10-27-17-33/h2-4,6-10,12,14-17H,1,5,11,13H2,(H,29,34)(H2,28,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene CAR LLC US Patent					Assay Description Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...				US Patent US10596172 (2020) BindingDB Entry DOI: 10.7270/Q2VM4G9X
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM397247 (US10596172, Compound I-204 | US10828300, Compound ...) Show SMILES Fc1cnc(Nc2cccc(OCCCn3ccnc3)c2)nc1Nc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C25H24FN7O2/c1-2-23(34)29-18-6-3-7-19(14-18)30-24-22(26)16-28-25(32-24)31-20-8-4-9-21(15-20)35-13-5-11-33-12-10-27-17-33/h2-4,6-10,12,14-17H,1,5,11,13H2,(H,29,34)(H2,28,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene CAR LLC US Patent					Assay Description Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...				US Patent US10828300 (2020) BindingDB Entry DOI: 10.7270/Q2JS9THK
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM397247 (US10596172, Compound I-204 | US10828300, Compound ...) Show SMILES Fc1cnc(Nc2cccc(OCCCn3ccnc3)c2)nc1Nc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C25H24FN7O2/c1-2-23(34)29-18-6-3-7-19(14-18)30-24-22(26)16-28-25(32-24)31-20-8-4-9-21(15-20)35-13-5-11-33-12-10-27-17-33/h2-4,6-10,12,14-17H,1,5,11,13H2,(H,29,34)(H2,28,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...				Citation and Details BindingDB Entry DOI: 10.7270/Q2X92FHZ
					More data for this Ligand-Target Pair