Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM441033'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM441033 (US10640486, Example 80) Show SMILES Nc1nccc2[C@@H](CCc12)NC(=O)c1cnn(Cc2cnc(nc2)N2CC3CC3C2)c1 |r| Show InChI InChI=1S/C22H24N8O/c23-20-18-1-2-19(17(18)3-4-24-20)28-21(31)16-8-27-30(12-16)9-13-6-25-22(26-7-13)29-10-14-5-15(14)11-29/h3-4,6-8,12,14-15,19H,1-2,5,9-11H2,(H2,23,24)(H,28,31)/t14?,15?,19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...				US Patent US10640486 (2020) BindingDB Entry DOI: 10.7270/Q2X92F98
					More data for this Ligand-Target Pair