Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50012087'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50012087 (CHEMBL3263648) Show SMILES Cc1ccc(cc1NC(=O)c1ccc(cc1)C(C)(C)C)-c1nc(Nc2ccc(cc2)C(=O)N2CCOCC2)c2nc[nH]c2n1 Show InChI InChI=1S/C34H35N7O3/c1-21-5-6-24(19-27(21)38-32(42)22-7-11-25(12-8-22)34(2,3)4)29-39-30-28(35-20-36-30)31(40-29)37-26-13-9-23(10-14-26)33(43)41-15-17-44-18-16-41/h5-14,19-20H,15-18H2,1-4H3,(H,38,42)(H2,35,36,37,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of full length human wild type his-tagged BTK expressed in Sf9 cells using biotinylated peptide as substrate after 1 hr by Fluorescence as...				Bioorg Med Chem Lett 24: 2206-11 (2014) Article DOI: 10.1016/j.bmcl.2014.02.075 BindingDB Entry DOI: 10.7270/Q2K075TC
					More data for this Ligand-Target Pair