Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50068603'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50068603 (CHEMBL3402357) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(NC(C)=O)c2)CC1 Show InChI InChI=1S/C21H26N4O2/c1-16(26)22-19-4-3-5-20(14-19)23-21(27)18-8-6-17(7-9-18)15-25-12-10-24(2)11-13-25/h3-9,14H,10-13,15H2,1-2H3,(H,22,26)(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Carna Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of biotinylated and unactivated BTK (unknown origin) using FITC-labeled Srctide peptide substrate and ATP				Bioorg Med Chem Lett 25: 2033-6 (2015) Article DOI: 10.1016/j.bmcl.2015.04.001 BindingDB Entry DOI: 10.7270/Q2VX0J60
					More data for this Ligand-Target Pair