Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase HCK' and Ligand = 'BDBM473701'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM473701 (US10844077, Compound I-1) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(CN3CCOCC3)nc(N[C@H]3CCN(C3)C(=O)C=C)n2)s1 |r| Show InChI InChI=1S/C27H31ClN8O3S/c1-3-23(37)36-8-7-18(16-36)30-26-31-19(15-35-9-11-39-12-10-35)13-22(32-26)33-27-29-14-21(40-27)25(38)34-24-17(2)5-4-6-20(24)28/h3-6,13-14,18H,1,7-12,15-16H2,2H3,(H,34,38)(H2,29,30,31,32,33)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute, Inc. US Patent					Assay Description The inhibitory activities of exemplary compounds described herein against select protein kinases.				US Patent US10844077 (2020) BindingDB Entry DOI: 10.7270/Q2862KJ4
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