Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase HCK' and Ligand = 'BDBM50451489'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM50451489 (CHEMBL4216163) Show SMILES Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)[C@H]1CC[C@@H](CC1)N[C@@H](Cc1ccccc1)C(O)=O |r,wU:23.26,wD:26.33,30.35,(20.09,-15.9,;20.09,-17.44,;18.77,-18.22,;18.77,-19.76,;20.1,-20.53,;21.44,-19.75,;22.91,-20.22,;23.82,-18.96,;22.9,-17.72,;23.37,-16.25,;24.88,-15.93,;25.34,-14.47,;24.3,-13.33,;24.77,-11.86,;26.27,-11.52,;27.31,-12.67,;28.81,-12.34,;29.27,-10.87,;28.23,-9.73,;26.73,-10.06,;22.79,-13.67,;22.33,-15.13,;21.43,-18.21,;23.4,-21.68,;24.91,-21.98,;25.39,-23.45,;24.36,-24.6,;22.85,-24.29,;22.37,-22.83,;24.83,-26.06,;26.33,-26.37,;26.81,-27.83,;28.31,-28.15,;28.78,-29.6,;30.28,-29.92,;31.3,-28.78,;30.82,-27.32,;29.32,-27.01,;27.36,-25.23,;28.86,-25.55,;26.88,-23.78,)| Show InChI InChI=1S/C33H33N5O3/c34-31-30-28(23-11-17-27(18-12-23)41-26-9-5-2-6-10-26)20-38(32(30)36-21-35-31)25-15-13-24(14-16-25)37-29(33(39)40)19-22-7-3-1-4-8-22/h1-12,17-18,20-21,24-25,29,37H,13-16,19H2,(H,39,40)(H2,34,35,36)/t24-,25-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN Center for Life Science Technologies Curated by ChEMBL					Assay Description Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assay				Bioorg Med Chem Lett 27: 4994-4998 (2017) Article DOI: 10.1016/j.bmcl.2017.10.012 BindingDB Entry DOI: 10.7270/Q2X92DV1
					More data for this Ligand-Target Pair