Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK' and Ligand = 'BDBM26887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM26887 (2-aminobenzimidazole with trans-stilbene, 9h | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)C(C)=Cc3ccncc3)nc2c1 |w:31.33| Show InChI InChI=1S/C31H28N6O3S/c1-20(18-21-12-15-33-16-13-21)26-10-11-27(41-26)29(39)35-31-34-24-19-23(8-9-25(24)37(31)17-14-28(32)38)36(2)30(40)22-6-4-3-5-7-22/h3-13,15-16,18-19H,14,17H2,1-2H3,(H2,32,38)(H,34,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	7.0	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair