Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50466038 (CHEMBL4281823) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University/Collaborative Innovation Center of Biotherapy Curated by ChEMBL | Assay Description Inhibition of recombinant human Itk (352 to 617 residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by sci... | J Med Chem 61: 11398-11414 (2018) Article DOI: 10.1021/acs.jmedchem.8b01652 BindingDB Entry DOI: 10.7270/Q2377CDJ | |||||||||||
More data for this Ligand-Target Pair |