Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM107141'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM107141 (US8592415, 26) Show SMILES FC(F)(F)C(=O)CC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H12F3N3O2/c19-18(20,21)16(25)9-17(26)23-12-5-3-4-11(8-12)15-10-22-13-6-1-2-7-14(13)24-15/h1-8,10H,9H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
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