Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM141490'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM141490 (US8921368, 314) Show SMILES C[C@]1(O)CCCC[C@@H]1Nc1c(cnn2cc(cc12)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C21H24N4O2/c1-21(27)10-6-5-9-18(21)24-19-16(20(22)26)12-23-25-13-15(11-17(19)25)14-7-3-2-4-8-14/h2-4,7-8,11-13,18,24,27H,5-6,9-10H2,1H3,(H2,22,26)/t18-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17.4	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substr...				US Patent US8921368 (2014) BindingDB Entry DOI: 10.7270/Q2HH6HS7
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