Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM279846'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM279846 (US10028960, Example 3-1 | US10485803, Example 3-1 ...) Show SMILES COc1cc(Nc2cc(CO)[nH]n2)nc(N[C@H]2C[C@@H]3CCC[C@H](C2)N3C(=O)C(F)F)n1 |r,TLB:25:24:21.20.19:16.23.17| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.550	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...				US Patent US10028960 (2018) BindingDB Entry DOI: 10.7270/Q23N25D9
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM279846 (US10028960, Example 3-1 | US10485803, Example 3-1 ...) Show SMILES COc1cc(Nc2cc(CO)[nH]n2)nc(N[C@H]2C[C@@H]3CCC[C@H](C2)N3C(=O)C(F)F)n1 |r,TLB:25:24:21.20.19:16.23.17| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP7836
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM279846 (US10028960, Example 3-1 | US10485803, Example 3-1 ...) Show SMILES COc1cc(Nc2cc(CO)[nH]n2)nc(N[C@H]2C[C@@H]3CCC[C@H](C2)N3C(=O)C(F)F)n1 |r,TLB:25:24:21.20.19:16.23.17| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...				US Patent US10485803 (2019) BindingDB Entry DOI: 10.7270/Q2XP779G
					More data for this Ligand-Target Pair