Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM475700'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM475700 ((4aR,8aS)-8a-ethyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4...) Show SMILES CC[C@]12CN(CC[C@H]1CCN(C2)c1ncnc2[nH]ccc12)C#N |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
LEO Pharma A/S US Patent					Assay Description Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...				US Patent US10851116 (2020) BindingDB Entry DOI: 10.7270/Q24B34DG
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM475700 ((4aR,8aS)-8a-ethyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4...) Show SMILES CC[C@]12CN(CC[C@H]1CCN(C2)c1ncnc2[nH]ccc12)C#N |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
LEO Pharma A/S US Patent					Assay Description Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK...				US Patent US10851116 (2020) BindingDB Entry DOI: 10.7270/Q24B34DG
					More data for this Ligand-Target Pair