Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM475711 (6-[(3aS,7aS)-3a-methyl-5-(7H-pyrrolo[2,3-d]pyrimid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
LEO Pharma A/S US Patent | Assay Description Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK... | US Patent US10851116 (2020) BindingDB Entry DOI: 10.7270/Q24B34DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM475711 (6-[(3aS,7aS)-3a-methyl-5-(7H-pyrrolo[2,3-d]pyrimid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
LEO Pharma A/S US Patent | Assay Description Inhibition of phosphorylation of a synthetic peptide was measured in an HTRF-based assay using the TK substrate-Biotin from the Cisbio HTRFKinEASE TK... | US Patent US10851116 (2020) BindingDB Entry DOI: 10.7270/Q24B34DG | |||||||||||
More data for this Ligand-Target Pair |