Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50124210'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50124210 (CHEMBL3622834) Show SMILES NCCn1c(nc2cc(ccc12)C(N)=O)-c1ccc(O)cc1 Show InChI InChI=1S/C16H16N4O2/c17-7-8-20-14-6-3-11(15(18)22)9-13(14)19-16(20)10-1-4-12(21)5-2-10/h1-6,9,21H,7-8,17H2,(H2,18,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Konkuk University Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin) using 87 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assay				J Med Chem 58: 7596-602 (2015) Article DOI: 10.1021/acs.jmedchem.5b01263 BindingDB Entry DOI: 10.7270/Q2H70HND
					More data for this Ligand-Target Pair