Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50135128'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50135128 (CHEMBL3745954) Show SMILES COc1ccc(F)c(c1)-c1nc2c(NCC3CCNCC3)c(Cl)cnc2[nH]1 Show InChI InChI=1S/C19H21ClFN5O/c1-27-12-2-3-15(21)13(8-12)18-25-17-16(14(20)10-24-19(17)26-18)23-9-11-4-6-22-7-5-11/h2-3,8,10-11,22H,4-7,9H2,1H3,(H2,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-fused human recombinant JAK1 (866 to 1154 residues) expressed in insect cells using FITC-C6-KKHTDDGYMPMSPGVA-NH2 as subs...				Bioorg Med Chem Lett 26: 60-7 (2015) Article DOI: 10.1016/j.bmcl.2015.11.031 BindingDB Entry DOI: 10.7270/Q2Z60QWQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50135128 (CHEMBL3745954) Show SMILES COc1ccc(F)c(c1)-c1nc2c(NCC3CCNCC3)c(Cl)cnc2[nH]1 Show InChI InChI=1S/C19H21ClFN5O/c1-27-12-2-3-15(21)13(8-12)18-25-17-16(14(20)10-24-19(17)26-18)23-9-11-4-6-22-7-5-11/h2-3,8,10-11,22H,4-7,9H2,1H3,(H2,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of JAK1 in human NCI-H1975 cells assessed as reduction in STAT3 phosphorylation after 2 hrs				Bioorg Med Chem Lett 26: 60-7 (2015) Article DOI: 10.1016/j.bmcl.2015.11.031 BindingDB Entry DOI: 10.7270/Q2Z60QWQ
					More data for this Ligand-Target Pair