Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [850-1154]' and Ligand = 'BDBM349000'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 [850-1154] (Homo sapiens (Human))	BDBM349000 (N-(5-(4-(2- (methyl(phenyl)amino)-2- oxoethoxy)phe...) Show SMILES CN(C(=O)COc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12)c1ccccc1 Show InChI InChI=1S/C25H23N5O3/c1-29(19-6-3-2-4-7-19)23(31)16-33-20-14-12-17(13-15-20)21-8-5-9-22-26-25(28-30(21)22)27-24(32)18-10-11-18/h2-9,12-15,18H,10-11,16H2,1H3,(H,27,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...				US Patent US10206907 (2019) BindingDB Entry DOI: 10.7270/Q23J3G3B
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