Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [861-1152]' and Ligand = 'BDBM50069328'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 [861-1152] (Homo sapiens (Human))	BDBM50069328 (CHEMBL3403539 | US9688661, 4-(6-aminopyrimidin-4-y...) Show SMILES Cc1ccc(Cl)cc1-n1cc(cc1C(N)=O)-c1cc(N)ncn1 Show InChI InChI=1S/C16H14ClN5O/c1-9-2-3-11(17)5-13(9)22-7-10(4-14(22)16(19)23)12-6-15(18)21-8-20-12/h2-8H,1H3,(H2,19,23)(H2,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	595	n/a	n/a	n/a	n/a	n/a	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description Assays were performed with the JAK1 kinase domain (residues 861-1152 of the 1154 amino acid long full-length sequence, accession number P23458 of Uni...				US Patent US9688661 (2017) BindingDB Entry DOI: 10.7270/Q2K35RTP
					More data for this Ligand-Target Pair