Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM127761'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM127761 (US8791123, 134 | US9782415, Example 134 | US979672...) Show SMILES FC(F)CNC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1 |r| Show InChI InChI=1S/C18H17F3N6O/c19-12-6-11(7-22-8-12)14-2-1-4-26(14)16-3-5-27-17(25-16)13(9-24-27)18(28)23-10-15(20)21/h3,5-9,14-15H,1-2,4,10H2,(H,23,28)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US9782415 (2017) BindingDB Entry DOI: 10.7270/Q2P84F0G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM127761 (US8791123, 134 | US9782415, Example 134 | US979672...) Show SMILES FC(F)CNC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1 |r| Show InChI InChI=1S/C18H17F3N6O/c19-12-6-11(7-22-8-12)14-2-1-4-26(14)16-3-5-27-17(25-16)13(9-24-27)18(28)23-10-15(20)21/h3,5-9,14-15H,1-2,4,10H2,(H,23,28)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array Biopharma, Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US8791123 (2014) BindingDB Entry DOI: 10.7270/Q2Q23XX7
					More data for this Ligand-Target Pair