Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332788'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332788 (US10196390, Compound I-61) Show SMILES Fc1cccc(F)c1-c1nc2CNC(=O)c2c(Nc2ccc(CC(=O)N[C@@H]3CCCNC3)cc2)n1 |r| Show InChI InChI=1S/C25H24F2N6O2/c26-17-4-1-5-18(27)21(17)23-32-19-13-29-25(35)22(19)24(33-23)31-15-8-6-14(7-9-15)11-20(34)30-16-3-2-10-28-12-16/h1,4-9,16,28H,2-3,10-13H2,(H,29,35)(H,30,34)(H,31,32,33)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
					More data for this Ligand-Target Pair