Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332887 (US10196390, Compound I-176) Show SMILES CC[C@]1(CCNC1=O)c1ccc(Nc2nc(nc3CNC(=O)c23)-c2c(F)cccc2F)cc1 |r| Show InChI InChI=1S/C24H21F2N5O2/c1-2-24(10-11-27-23(24)33)13-6-8-14(9-7-13)29-21-19-17(12-28-22(19)32)30-20(31-21)18-15(25)4-3-5-16(18)26/h3-9H,2,10-12H2,1H3,(H,27,33)(H,28,32)(H,29,30,31)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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