Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332969'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332969 (US10196390, Compound I-258) Show SMILES COc1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2C#N)nc1 Show InChI InChI=1S/C20H14FN5O2/c1-28-12-5-6-17(23-9-12)26-15-7-14(25-16-10-24-20(27)19(15)16)18-11(8-22)3-2-4-13(18)21/h2-7,9H,10H2,1H3,(H,24,27)(H,23,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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