Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332973'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332973 (US10196390, Compound I-262) Show SMILES Fc1cccc(F)c1-c1cc(Nc2ccc(cn2)N2CCN(CCC(F)(F)F)CC2)c2C(=O)NCc2n1 Show InChI InChI=1S/C25H23F5N6O/c26-16-2-1-3-17(27)22(16)18-12-19(23-20(33-18)14-32-24(23)37)34-21-5-4-15(13-31-21)36-10-8-35(9-11-36)7-6-25(28,29)30/h1-5,12-13H,6-11,14H2,(H,32,37)(H,31,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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