Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332976'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332976 (US10196390, Compound I-265) Show SMILES C[C@@H]1CCC[C@@H](C)N1c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 |r| Show InChI InChI=1S/C25H25F2N5O/c1-14-5-3-6-15(2)32(14)16-9-10-22(28-12-16)31-20-11-19(23-17(26)7-4-8-18(23)27)30-21-13-29-25(33)24(20)21/h4,7-12,14-15H,3,5-6,13H2,1-2H3,(H,29,33)(H,28,30,31)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
					More data for this Ligand-Target Pair