Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332983'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332983 (US10196390, Compound I-272) Show SMILES CC1(C)CCC(=O)N1c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 Show InChI InChI=1S/C24H21F2N5O2/c1-24(2)9-8-20(32)31(24)13-6-7-19(27-11-13)30-17-10-16(21-14(25)4-3-5-15(21)26)29-18-12-28-23(33)22(17)18/h3-7,10-11H,8-9,12H2,1-2H3,(H,28,33)(H,27,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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