Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332988'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332988 (US10196390, Compound I-277) Show SMILES FC(F)S(=O)(=O)Nc1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 Show InChI InChI=1S/C19H13F4N5O3S/c20-10-2-1-3-11(21)16(10)12-6-13(17-14(26-12)8-25-18(17)29)27-15-5-4-9(7-24-15)28-32(30,31)19(22)23/h1-7,19,28H,8H2,(H,25,29)(H,24,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
					More data for this Ligand-Target Pair